Other mistake: During the opening scene, basic explosive physics dictates that the car should have moved away from the meteor crash, not up and over it.
Plot hole: Because humans have a layer of subcutaneous fat under the skin, the bug that travels under Harry's skin would have caused not only significant damage but an amazing amount of pain while moving around. There would have also been severe internal damage caused by the bug if it traveled into his colon where they ended up removing it from.
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