Continuity mistake: When Dr. Sayer and the group of patients are in the dance hall, he is sitting at a table with a drink. He picks up a cherry that is lying on a napkin near the drink and eats it. One of the female patients asks him to dance, and as he gets up the cherry has reappeared on the napkin.
The drug wears off, and the patients all go back to their comatose state, including Robert DeNiro. Robbin Williams is nonetheless encouraged, since he at least discovered what the illness was. He finally invites the nurse out for coffee.
Dr. Sayer: I'm sorry, if you were right, I would agree with you.
Trivia: During the scene where Robin Williams (the doctor) has to restrain Robert DeNiro (the patient), Robin accidentally broke DeNiro's nose. DeNiro insisted that they continue with the filming until the scene was completed because he knew, from prior experience, that he wouldn't be able to film for at least a week, until the swelling and bruising went down. And DeNiro actually was glad it happened because it corrected the bump from the prior broken nose.
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