The movie begins in the 1930's, when Robert DeNiro is a boy, who slowly starts disconnecting with the world, and goes into a sort of canatonic state. Flash ahead about 30 years later in the 1960's, Robin Williams is a pschiatrist who starts at a mental hospital, the same hospital that a catatonic DeNiro is at. Robin Williams starts experimenting with a drug mixture, that eventually awakens the catatonic patients, including DeNiro. DeNiro eventually awakens and starts to experience life with Robin Williams. DeNiro also starts to fall for a young woman, who seems to like him too, but then things start to go down hill for DeNiro. He starts exibiting unusual signs, like scratching his tempal a lot and severe shaking. Eventually good things do not last very long.