Continuity mistake: When inspecting the plane for damage, the propeller changes position without being touched. The side by Alice goes from the 8 o'clock position to the 10 o'clock position. (00:34:30)
Continuity mistake: The bullet holes in the doors the two Alice clones dive through near the start are constantly changing place. (00:11:05)
Continuity mistake: During the initial fight scene, one of the Alice clones takes cover behind a pillar, which is fully intact. When the shot cuts to show her and the other clone, there are three bullet holes that have mysteriously appeared in the pillar. (00:11:10)
Answer: Wesker needed to consume fresh DNA to help control the T-virus. He was eating people who had been captured. This scared the crew enough to abandon ship.
LorgSkyegon