Continuity mistake: When Luther ducks to avoid getting hit by Alice's plane, his gun falls out of his pants. He then picks it up again just before he runs off to clear the roof. But in the shot where Angel runs away, his gun is still lying in the middle of the "E." (00:30:20)

Resident Evil: Afterlife (2010)
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Directed by: Paul W.S. Anderson
Starring: Milla Jovovich, Ali Larter, Kim Coates, Wentworth Miller
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Trivia: Leon Kennedy, a popular character from the games, was originally intended to be in the film but was dropped. He later appeared in the fifth film.
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Answer: Based on the sounds to go with the scene, I'd say it is zombies taking the guards out. However, considering following events it is more likely that Alice and her friends have something to do with it.