Factual error: In the lab in Hong Kong Croft is in a gunfight against Til Schweiger and another baddie. She makes a leap, kills one guy and takes cover behind a table. Then she engages the slide locks and comes up to kill Till Schweiger. All this makes no sense because if the slides were locked backed after the first kill, the guns were empty. This means that she came out of her cover with two empty guns because she didn't reload them before but just engaged the slide locks. If she did in fact reload offscreen it still would make no sense because when she sees Schweiger's trap, she doesn't let off a single round but still reloads as soon as she is behind the table again. In this case she would have replaced two full magazines with two other full magazines.
Factual error: When Lara is hooking up her phone and camera to the T.V. on the boat, she goes around back and flips off a cover to reveal wires. However, when she attaches her clip to a red wire, she clips it to the plastic coating instead of the bare wire itself. In real life, there would be no current able to go through the plastic.
Factual error: For the scene in Shanghai, they actually used Hong Kong cars, the Isuzu truck and the Mercedes S-class, as the cars are right-hand-drive, like Hong Kong, while in China cars are left-hand-drive. Also the license plates are not real. The helicopter in the same scene is one that belongs to the Heli-Services in Hong Kong, painted black.
Factual error: When Lara walked into Times Square in Hong Kong and looked up to the skylight: there is no skylight - just a ceiling in that building. Also had the shootout really taken place, dozens of police officers would have been at the crime scene within minutes, as you have policemen at every street corner.