Audio problem: When Wendy and Jules are talking in the bathroom, two women walk by and say "Hi Leslie" and "Hi Les, how ya doing?" to Leslie. It is easy to see that their mouths do not move in sync with the words that are heard.
Continuity mistake: In the bar scene when Billy is playing the saxophone on stage, his wife enters the bar with her boyfriend. The saxophone music keeps playing after Billy starts glaring at them, even though Billy has stopped blowing air into the horn and is not pushing the horn's buttons.
Continuity mistake: In the scene where Demi Moore drives Rob Lowe home in her jeep, Demi is wearing white, long earrings. When she tuns to talk to Rob Lowe she has both on them on. When they cut to him and then go back to her she only has one on. Then, again they cut back to Rob Lowe and then back to Demi, she has both of them on again.
Continuity mistake: At end of the movie, Rob Lowe lights two cigarettes when he is in Demi Moore's bedroom. He offers Demi one and she refuses. Rob the takes a cap and puts out of the cigarette, but now the other cigarette he lit is completely disappeared. There is only one cigarette resting in the cap and he does not have the other one in his hand.
Factual error: When Kirby sees Dale at the ER, he says "You were a senior when I started at Georgetown." That's just three years between them and the gang just graduated from Gtown a few months ago. Dale should still be in med school, years away from becoming a doctor.