Factual error: The cockpit voice recording is highly sensitive in nature. It would never be played in front of hundreds of people like in the movie.
Factual error: The NTSB was portrayed horribly in this movie. They investigate purely on facts, not going on witch hunts like this movie implies. In the movie they tried to "second guess" and "blame the pilot." This never happens in real life.
Continuity mistake: During passenger boarding the screen (Flight Attendant Panel), located above the forward flight attendant seats is a newer touchscreen one, but when flight attendants are doing safety demo, it changes to the older LED push button type.
Continuity mistake: When they are evacuating passengers onto the ferry boat, a crew member puts his hat on a passenger in a white shirt. In the next shot and when he says that he is cold he is not wearing a hat. In the very next shot the hat is back on.
Factual error: The movie showed the FAA HQ building. Then the next shot showed the NTSB Public Hearing Room. The NTSB is actually located around the corner in DC from the FAA. They are not in the same building.
Factual error: When the A320 taxies out from LaGuardia there is a Continental airlines jet with scimitar winglets. These were not on commercial aircraft in 2009.