Factual error: The cockpit voice recording is highly sensitive in nature. It would never be played in front of hundreds of people like in the movie.
Factual error: The NTSB was portrayed horribly in this movie. They investigate purely on facts, not going on witch hunts like this movie implies. In the movie they tried to "second guess" and "blame the pilot." This never happens in real life.
Factual error: The movie showed the FAA HQ building. Then the next shot showed the NTSB Public Hearing Room. The NTSB is actually located around the corner in DC from the FAA. They are not in the same building.
Factual error: When the A320 taxies out from LaGuardia there is a Continental airlines jet with scimitar winglets. These were not on commercial aircraft in 2009.