Trivia: None of the moths seen in the film are actual Death Head moths. In the interest of avoiding the hassle involved with actually shipping moth eggs over, then halting filming so they could be raised to the proper level of maturity, the production crew simply went with a similar looking domestic breed of moth, and glued false fingernails painted with the trademark skull like visage onto their bodies.
Trivia: Buffalo Bill was based on three real serial killers: Ed Gein, who skinned his victims and wore the skin; Ted Bundy, who wore a cast to appear crippled and lure unsuspecting, sympathetic women; Gary Heidnick, a man who kept the women he abducted in a pit in his basement.
Trivia: In the movie, Buffalo Bill cocks his revolver and inadvertently warns Clarice he is about to fire. The book explains this was a part of his ritual to terrorize his victims before killing them. He would follow them in the dark basement until his got bored and then cock his gun so they'd know they were about to die. He expected Clarice to react the same, but she instinctively shot him before he realised what was happening. (01:49:00)
Trivia: The female dead body in the funeral home was a real actress, not a mannequin. Because the bug cocoon would be placed in her mouth until it is taken out in the middle of the examination, the prop master made the bug cocoon out of a mixture of tootsie rolls and gummie bears. This way if she accidentally swallowed it, it wouldn't do her any harm.
Trivia: FBI agent John Douglas made Scott Glenn (the actor who plays Jack Crawford) cry, when Glenn was at the Behavioral Sciences Unit (now called Investigative Support Unit) in Quantico, Virginia. He played a tape (sound, not video) of killers Lawrence Bittaker and Roy Norris torturing, raping and killing young girls (between 13-18 years old) in the back of their van. Before the encounter, Glenn was firmly against capital punishment.
Trivia: During the film's production, while Anthony Hopkins was playing Hannibal Lecter, Brian Cox (who played the character in "Manhunter") was playing King Lear at the National Theater. Ironically, during the production of "Manhunter" five years earlier, Hopkins was playing King Lear at the same theater.
Trivia: The role of Hannibal Lecter was originally supposed to go to Gene Hackman, who bought the rights to the source novel and had planned on directing the film himself. He backed off the project when he decided that the role was too dark for his taste, and he felt that he had already played an unlikeable character in "Mississippi Burning."