Continuity mistake: When they find out Lecter is on the elevator, they look down the shaft at him and there is quite a lot of blood on his back, so much that it even reaches down to his belt. However when they open the elevator shaft and the body falls down, there is only a small amount of blood on his back. (01:23:40 - 01:24:50)
Factual error: Many of the vehicles in the movie have Pennsylvania inspection stickers on the lower driver's side windshield. This is not surprising being that most of the movie was filmed in Pennsylvania. However, they should have been removed when the car is suppose to be from another state. For example, the Senator's daughter, just before her abduction in Tennessee, is seen driving a car with Pennsylvania inspection stickers. Also, the driver for Yourself Storage in Baltimore also has Pennsylvania stickers on his car.
Continuity mistake: When Clarice is searching the basement, the first door she approaches is hinged on the left and opens towards her. She opens it, and it turns into a door that has the hinges on the right and opens away from her. (01:43:50)cinecena
Continuity mistake: At the beginning when Clarice is jogging through the woods, the sweat on her sweatshirt varies from shot to shot.
Character mistake: A SWAT officer gets the go-ahead to use his Browning HP to shoot an unconscious Lecter (actually Pembry) in the leg to immobilize him. he fires the pistol extremely close in proximity to his face, something a real officer would not do, as the motion of the slide would harm or burn his face and he could very nearly go deaf. (01:24:05)Joey221995
Revealing mistake: When Clarice is at the archive, she sees two articles, one entitled "Baltimore Psychiatrist Receives Highest Honor" and "New horrors in 'Cannibal Trial'." The column beneath both titles to the right is exactly the same, and in the first article, that same column is repeated at the leftmost and rightmost columns and in the second, is repeated at the rightmost column. That same column is scattered on every article she sees. (00:21:35)
Continuity mistake: While travelling from the post mortem examination, Clarice is in the back seat speaking to her boss. In going back and forth in conversation, her hair changes from being curled up to being curled under, all in one swift change. This is a different style and not done as could be by running your fingers through your hair as the camera cut away. (00:37:45)
Revealing mistake: During Lecter's escape, the SWAT team arrives and jumps out of the police car at the courthouse with their Ithaca 37 shotguns. All of them are shown chambering their rounds except the the officer on the right, who pulls back again on the fore stock and asks "ready?" That should've ejected a shell and left the gun unloaded. (01:21:40)Joey221995