Continuity mistake: On the ferry, Rachel wears the purple/pink camouflage hoodie over her orange knit sweater with the colorful stripe sleeves, as usual. Now this is where things become strange. In the first shot as the trio come ashore, she is only wearing her orange sweater, she is not wearing the purple/pink hoodie - note the clear lack of fur hood. In the very next shot as they climb a bit more and then rest, Rachel is wearing the purple/pink hoodie - note the hood, but now it's on under her orange sweater. In the underwater shots she is also wearing it under the orange sweater. (This odd mistake has absolutely nothing to do with the very long wool cloak that Rachel wears in the next scene). (01:02:20 - 01:04:40)
Deliberate mistake: Gandu Three Echo, the clone who hits the screen showing the first lottery winner in the movie, complains that he has been around for 7 years and never won the lottery. However, McCord explains later in the movie that the last name tells how old the clones are. Lincoln Six Echo is 3 years old because he is in the Echo generation, and the Delta generation (Jordan Two Delta) is 4 years old. Going backwards, this would make Charlies 5 years old, Bravos 6 years old, and Alphas 7 years old. Gandu Three Echo should have really been Gandu Three Alpha. (00:05:55)
Character mistake: In the scene where Steve and Josie prepare to leave to fight the giant robot at the beginning of the movie, Steve tells Will "Oh, Will, a reminder: a lot of the kids at Sky High will only have one super hero parent, not two." When he says "one super hero parent", he holds up two fingers. When he says "not two", he holds up only one finger.
Continuity mistake: When John is driving to work and he hears Anna on the radio, he swerves to avoid a car. From inside the car you can see that there are no cars in the rear window, yet when the shot changes to an outside shot, there are 3 cars. (00:33:35)
Visible crew/equipment: When the woman is performing an autopsy on one of the dead "creatures" the lights supposedly flicker and turn off. There is a hand visible flicking the switches on the lamp to the right side of the screen. (00:45:40)
Factual error: There would not be so many people standing around on the flight deck without some type of ear and eye protection and a float coat.
Continuity mistake: In the scene where Chicken Little lends the alien baby, Kirby, his handkerchief, after Kirby blows his nose, it sticks to Chicken Little's hand. Chicken Little then wipes the hanky off his hand on to the grass. In the very next shot, the hanky has disappeared, and never shows up again.
Continuity mistake: Following Rodney's step from the escalator on the red pedestal he is being scooped into one half of a wire-frame globe/ball. Two halves now (the other one has Fender in it) form an intact globe. A safety bar with a 'wooden' middle bit (like those on rollercoasters) suddenly appears. After their journey, when the ball splits back into two halves, the safety bar, which previously had mysteriously appeared, now has disappeared.
Continuity mistake: When the cast are at the Miranda colony and discover that everyone is dead, there is a rotating shot of River as she realises what happened. Prior to this there is a brief closeup shot of the rest of the cast as they turn to face her. Jayne turns to his right, but in the following rotating shot of River he has turned from his left. (01:16:30)
Plot hole: In the course of the story it's said that at the time the black hole went out of control, it had a mass of "half a mountaintop of granite." But in a flashback scene Dr. Krone is shown growing the mass of the hole by feeding it large numbers of lead bricks in the laboratory. It's a little hard to believe his lab could store, or even afford, enough lead bricks to equal that much mass.
Continuity mistake: When Johnny is walking out of the dirt bike stadium, he has his arms around two women's shoulders. The shot changes, now the two women are holding on to his arms. The shot changes again, and now his arms are free. It happens too fast for him to just let go of the women. (01:00:35)