Trivia: At the beginning, the cabin looks very similar to the cabin in The Evil Dead, even the swinging bench (although on the opposite side of the door). And the girl calls out the name Ashleu, Bruce Campbell's character in Evil Dead.
Trivia: Dean dies 10 different ways in this episode. 1. Shot in the chest. 2. Hit by car. 3. Heavy piece of furniture dropped on head. 4. Chokes on piece of sausage. 5. Slips and falls in the shower. 6. Food poisoning. 7. Electrocuted. 8. Accidentally killed by Sam with an ax. 9. Attacked by a dog. 10. Killed by mugger.
Trivia: Ruby (Genevieve Cortese), is married to Jared Padalecki. They have 2 sons.
Trivia: The inscription on John Winchester's gun is Latin, translating to "I will not fear evil."
Trivia: Dean's guiding angel Castiel is also the angel of Thursday. Fitting, since Supernatural airs on Thursdays in the U.S.
Trivia: The Metallicar is a 4-door 327 4 barrel Small Block Engine 1967 Chevy Impala.
Trivia: In 'After School Special' Dean says the the regular gym teacher is getting married in Massachusetts. This is a reference to how female gym teachers are thought to be gay. At the time of the airing of this episode Massachusetts was the only state in the U.S. that allowed gay marriage.
Trivia: At The End of the episode, Dean says to Sam "hey did she look familiar?" Then says "are you hungry? I could go for some pea soup." He's referring to Linda Blair in the Exorcist. She played a cop in this episode.
Trivia: Sam and Dean are named after their mother Mary's parents, Samuel and Deanna.
Trivia: This episode marks the 300th episode of Supernatural.
Trivia: Jeffrey Dean Morgan plays John Winchester, father of Dean Winchester (Jensen Ackles). In real life, Morgan is only 12 years older than Ackles.
Ask Jeeves - S10-E6
Trivia: This episode is a nod to the game Clue. Each weapon appears in a shot. Dash grabs the revolver. Dean grabs the candlestick, wrench, lead pipe and rope. Phillip was stabbed by the knife. Also there is six people invited to the party, three men and three women, referencing the guests who usually attend the Clue game party.
Answer: Angels themselves may not have genitalia, but their vessels do. Nephilim occur when an angel in a vessel reproduces.
Greg Dwyer