Plot hole: At first the victim (Careful Lionel) is described as not returning to pick up his new shirt in November 1958, and possessing love letters dated from 1957 through early winter (November) 1958. Booth reports the fallout shelter where Lionel's body was discovered was sealed in 1958. Later Lionel is described as reported missing by his boss in January 1960, and the illegitimate child he fathered was born in 1960 as well. That would mean his boss didn't notice he was gone for over a year, and his pregnant girlfriend was with child for at least 14 months.
Plot hole: Angela comes into the autopsy room to inform Hodgins and Cam that Brennan is awake. Cam says that Brennan said the entry wound was cold and Hodgins comes up with the ice bullet theory. But how did Cam know what Brennan said about the cold if she didn't already know Brennan was awake?
Plot hole: In the beginning of the episode Booth is brought in by ambulances because he was shot. The episode flashes back and follows back through the events leading up to that. At the end of the episode he is arrested and accused of murdering 3 FBI agents who were coming "to serve warrants." In actuality Delta Operatives had tried to kill Booth. If Booth had been picked up at the scene of the battle by paramedics, the medics would have seen the dead bodies of the operatives in their gear and been able to easily prove Booth didn't just murder 3 agents. Furthermore, the medics on the scene would not just ignore the destroyed house and dead bodies. They would have called local PD and Booth would again be off the hook.
00:01:00 - 00:46:00Mona Wheeler
Plot hole: The surgical instrument that killed 'Susan' was the same one used on her jaw during her plastic surgery. 'Leslie" would not have been able to get the instrument to use to murder her and then put it back in the case, since it was still in the office in the case when Bones and Booth came to get it.
Plot hole: We learn that Agent Booth has a brain tumor that has been causing him to hallucinate. One of the hallucinations mentioned was Parker in "The Hero in the Hold." At the end of the episode, Dr. Brennan both sees and speaks to Parker in the cemetery. Agent Booth believed Parker to be a ghost, and we were to believe that Dr. Brennan had unknowingly had a paranormal experience.
Add timeProfessor Plum
Plot hole: When doing the investigation they go to the construction site and speak to the foreman who is absolutely fine. However at the end, the foreman is unstable on his feet with a head injury. He should have been unstable when they first spoke to him.
Add timeA Demon
Plot hole: The bullet that killed the victim had plastic associated with the wound. This was explained by the fact that the bullet that killed the victim hit a lane divider as it entered the water, but at the end of the episode it was discovered that the bullet was fired from under the water, negating the possibility of it hitting a lane divider at the surface.