Factual error: The CSI crew set up an experiment. They put some chloroform into the tire, set the bus on a dynamometer (or some other testing platform) and wait for the tire to fail. The tire fails in the experiment in the exact same amount of time as it did in real life. Problem: They have no idea how much chloroform was used and it would be impossible to match it by luck. More chloroform used would equal quicker failure. Then, there is the heat. The tire traveling over the hot asphalt road would build heat faster then on their testing platform. More heat would mean a quicker failure, too.
Factual error: Sara calculates the time needed to sabotage the tire at a minute to a minute and a half. That is, remove the valve core, allow the majority of the air to escape (cannot pour anything into the tire while the air is escaping) pour in enough chloroform to sabotage the tire, replace the valve core, and air the tire to pressure. Even with an industrial air compressor, it would take over 2 minutes to air that tire to full pressure.