[After saving Giles from a vampire.]
Spike: Awww, poor Watcher. Did your life flash before your eyes? Cup of tea, cup of tea, almost-got-shagged, cup of tea?
Seeing Red - S6-E19
Xander: I think it's the "daddy" thing that's throwing her. 'Cause incest? Not that sexy.
Xander: Hey now - play nice, fellas, or you'll break our concentration.
Anya: Which means no protection spell...
Xander: And Willow will make sure you two boneless chickens are skinless, too.
Andrew: Then what? You think your Li'l Witch buddy's gonna stop with us? You saw her! She's a truck driving Magic Mamma. We've got maybe seconds before Darth Rosenberg grinds everybody into Jawa burgers, and not one of you bunch has the midiclorians to stop her.
Xander: You've never had any tiny bit of sex, have you?
Tabula Rasa - S6-E8
Spike: Oh, listen to Mary Poppins. He's got his crust all stiff and upper with that nancy-boy accent. [Everyone looking at him.] You Englishmen are always so... [pauses.] Bloody hell! [Ticks off on his fingers.] Sodding, blimey, shagging, knickers, bollocks, oh God! I'm English!
Giles: Welcome to the nancy tribe.
Chosen answer: He had larangitis and because of the shooting specifications they had to have him shoot the scene with a bad throat, they then re-recorded his lines and dubbed them. At various points during the scene and indeed the episode you can see him touch his throat or rub it.