Continuity mistake: When Jennifer Walters is first introduced, her fingernails are unpolished. Later when she is restrained in Dr. Doom's lair, her fingernails alternate between being painted pink and red. Given that she and Bruce were running for their lives, she wouldn't have had time to paint her nails. Later when she transforms into She-Hulk, her fingernails turn green with the rest of her body, but if her fingernails were painted, they should still appear that color, as her skin and hair turning green wouldn't magically remove nail polish.
Continuity mistake: When Doc Samson tackles the new Rick Jones-Hulk hybrid and knocks over the cylinder for the nutrient bath, Banner spills out, and you can see he is wearing shoes. A few moments later when Banner begins to run outside, he is suddenly barefoot. (00:19:44 - 00:20:10)
Continuity mistake: When Dark Hulk arms the nuclear warhead, the orientation of the timer is the same as the control buttons. When Banner disarms the warhead, the orientation of the timer is now upside down respective to the control buttons. (00:18:00 - 00:20:26)
Continuity mistake: When She-Hulk is following Miss Allure's limousine, we see a shot of her hitting the gas pedal, and you can see the brake pedal next to it. When she is shown hitting the gas pedal again, the brake pedal is now missing and the gas pedal itself is larger than previously shown. (00:10:06)
Continuity mistake: When Banner re-engages Hulk in the desert after Hulk disposes of Talbot, the face guard for the exoskeleton armor Banner is using is missing, but then reappears when Banner launches the armor's right foot at the Hulk's backside. (00:07:38)