Continuity mistake: When Dr. Ross and Bruce are in the hotel room, Banner empties the purse on the bed and there is some cash inside the wallet. As they are about to leave he picks up the cash, which isn't in the wallet anymore. (01:08:10)
Continuity mistake: In the motel room, Betty gives Bruce a new heart monitor watch, still in its box. In a subsequent shot, the box has disappeared and Bruce is putting the watch on. The cut to Betty and back is too fast for him to have taken the watch out and junked the box. (01:04:10)
Trivia: Stan Lee (Stanley Martin Lieber), the original creator of this comic book hero, has his usual cameo role in this movie. He's the guy who drinks the gamma contaminated soda from the fridge.
Chosen answer: It's entirely self-containing - effectively the film acts as a relaunch of the franchise rather than a continuation, although it doesn't really have any continuity issues with the first.
Tailkinker ★