Continuity mistake: In a scene near the end of the movie, George enters the Building and Loan with a Christmas wreath on his arm. On hearing that he has a phone call from his brother Harry, he tosses the wreath on a table and picks up the phone. In the next second, the wreath is back on his arm. (01:17:35)
Continuity mistake: In a scene early on in the film, where George Bailey (James Stewart), Bert (Ward Bond) and Ernie (Frank Faylen) chat in the street, they suddenly stop due to the appearance of Violet (Gloria Grahame) in her "this is what I wear when I don't care how I look" dress. The camera cuts back to them and we see a dark haired woman in a hat pass in front of Ernie's taxi. As Violet crosses the street and gets honked at, we see another shot of the boys staring after her - and the dark haired woman passes in front of the taxi again.
Visible crew/equipment: When Mary leans across the drugstore counter to whisper in George's bad ear, there is a small piece of tape on the edge of the counter right in front of her hand, presumably to show the actors where to position themselves for the shot (the tape isn't visible in the other shots showing that same section of the counter). (00:06:55)
Continuity mistake: In the scene at the railway station where George and Uncle Billy are waiting for Harry, Billy reaches in the bag of peanuts and pulls one out. As the camera angle changes slightly, Billy's hand is suddenly back in the bag and pulls out another peanut. Also the man in the background wearing coveralls and a locomotive cap changes his position, and has lost the pamphlet he had just placed in his back pocket. (00:35:20)
Continuity mistake: When George is kicking stuff and knocking stuff over in his house (after yelling at his children), his hair is messed up. In the next shot, it's combed again.
Continuity mistake: During a confrontation between old man Potter and Peter Bailey at the Building and Loan, Potter's bodyguard stands behind the wheelchair on its left side. But in the close-up shot of Potter, the arms and hands of his bodyguard can be seen extending from the right side of the wheelchair. In the next full screen shot, the bodyguard is seen on the left side of the wheelchair once again.
Continuity mistake: In the confrontation scene between Peter Bailey and Old Man Potter, Peter moves from behind his desk about four feet away from Potter, to sitting on the edge of the desk about 18 inches away from Potter. Also the coat on the coat rack behind Potter changes from hanging from the collar loop to just the collar itself. (00:09:25)
Revealing mistake: When George is on the bridge and says "I wanna live again", and Burt drives up, in the shot where George hugs Burt, then Burt pats him on the back, you can see Burt's handprint in the fake snow that was used (a mixture of foamite soap and water) on the back of George's coat. (02:02:35)
Factual error: In the closing scene Ernie the cab driver is wearing a military shirt with an Air Force insignia on the sleeve, but we were told earlier that Ernie parachuted into France. His shirt should have had a different patch.