Continuity mistake: Cross screams Tracie's name as the cables give way and she begins to fall to her death. He is holding onto a large metal rod, but in the next shot he is holding the smaller branching part of the same guardrail. (00:04:55)
Continuity mistake: Morgan Freeman shouts to the agent in the car "Don't move! Stay where you are." She is looking at her bloodied hand in front of her face as she slowly turns around, but in the next shot the hand is gone. (00:04:35)
Continuity mistake: After Mercusio gets shot, Cross has to face the senator, who tells him "and you're telling me you haven't a clue?" The agent walking past is nowhere to be seen in the reverse shot that follows. (01:19:00)
Continuity mistake: Alex Cross is picking up the wet jumper found in the channel after the murder of the fisherman. He holds the neck of the garment straight and tense, but in the close-up it's loose and in a curve. (00:49:15)
Continuity mistake: The first time that Cross spots Jezzie Flanigan, he is holding the Soneji picture in front of him, chest-height. Reverse shot and he is holding the position, but with the picture belly-high. (00:19:45)
Continuity mistake: At Mercusio's place, one agent says he "was wearing prosthetic appliances." The reaction shot on Morgan Freeman shows him with a background that does not match the view of the room. (00:40:10)
Continuity mistake: Cross is about to shoot at the window of the train to break it; he is holding on to the vertical bar of the cart with the thermos hand, but the bar is gone in the closer view. (01:10:20)
Factual error: Outside of the house of Senator Rose are police cars of the Barcroft County Police. The police for Lake Barcroft are the Fairfax County police. (01:01:15)
Continuity mistake: To enter the Rose residence with the boot courtesy of Soneji, Cross shows the Fed at the door his badge with his left hand, that becomes the right at the cut. (00:18:45)
Continuity mistake: In front of the embassy, the driver's window jumps several times from being quite open, to closed (during the U turn) to less open (during the shootout). (00:58:00)
Continuity mistake: Jezzie points the gun at Devine's throat. When she begins laughing, she lowers the gun, which is still all the way up pressing to his jaw in the reverse shot. (01:24:00)
Continuity mistake: Cross tells the agent at the gates "I've been invited", and the man opens the door pulling it by the handle, which becomes the top of the door at the cut. (00:18:55)
Continuity mistake: Cross is at Union Station, and hears a public phone ring. When he dashes across the entrance, the passersby change between shots. (01:07:35)
Continuity mistake: Cross is making a model ship. Vickie makes a joke about being "ship-shape"; at cut, she has in her mouth a spoon she did not initially have. (00:12:30)
Continuity mistake: Dimitri hands Jezzie the knife between the gate bars; he is holding it in two different ways in the two shots. (00:59:35)
Continuity mistake: Jezzie pours the diamonds from the thermos into her left hand. In the close-up, she is pouring them again. (01:25:30)
Continuity mistake: Devine's cigarette burns half an inch the moment he turns the TV off (and we switch to the close-up). (01:23:05)
Continuity mistake: Megan takes Soneji's cup with her left hand, but drinks in the reverse shot with her right. (00:26:05)
Revealing mistake: There is a mistake in the (quite dodgy) CGI when the car tumbles down into the dam in the opening scene. At one point, the camera cuts and we can see the car bouncing downwards through the air, and there's a splash of water from where the car bounced off the wall of the dam. But if you pay attention, the splash of water simply vanishes/fades away about two seconds later. Sure, if it was more of a fine mist, it'd make sense that it'd lose visibility, but these were huge streaks of water that should still be visible for quite a bit longer.
Continuity mistake: The first time we see her, Jezzie is talking to Megan. She is holding her clipboard with the hand placed underneath it or above it depending on the angle. (00:05:40)