Continuity mistake: After Ron throws the burrito at the biker the exterior shot of the car shows he is in the middle of the three lanes. When it cuts to his reaction shot you can see he is now in the left lane. After showing the biker in agony we see Ron getting out of his car in the middle lane.
Continuity mistake: Right after Ron throws Veronica over the desk after she makes fun of his hair, she jumps on his back, and pins him to the floor. In the first shot of the floor, a purse is seen on Ron's right, but the in the next shot of the floor (where she picks up the mace) the purse is on his left.
Continuity mistake: Before the big brawl between the rival news crews there are a number of shots where the sun is nearly setting and a second or so later will be right back up. The most notable one is just after Ben Stiller's Spanish language crew arrive there is an aerial shot with the sun very bright. In the next shot of Tim Robbins the shadow has become much more noticeable.
Continuity mistake: Early in the movie, as Ron Burgundy is talking with his dog at his apartment, pay close attention to the suit jacket on the back of the chair. As the camera shifts between views of the dog and Ron, the coat moves around. In the final shot, when the dog jumps off the back of the chair, the coat is in yet a third position.
Continuity mistake: After the big fight scene with all the different news stations, Ron and his news team are all in the office thinking about what happened. Ron puts down a beer bottle at one point. In the first shot of this, the bottle is about half full. In the second shot, it is filled to the point where the curve in the bottle ends, which is more beer than there was in the first shot.