John W. Creasy (Denzel Washington) is a burned-out ex-CIA assassin, who is continously haunted by the sins that he has committed. His best friend Rayburn (Christopher Walken) gets him a job as a bodyguard for industrialist Samuel Ramos' (Marc Anthony) young daughter Pita (Dakota Fanning) and his wife Lisa (Radha Mitchell). At first Creasy sees Pita as only a job showing no interest in her whatsoever (except protecting her). But pretty soon he begins to show affection for her as she changes the cold and heartless man in Creasy, and gives him a new purpose in life. But the happiness is broken when Pita is kidnapped. This tragic event changes Creasy back to his old behaviour and he becomes determined to rescue her and kill everyone involved in the kidnapping.