Factual error: During the fight in the museum, Spartan gets three shots out of a shotgun which only holds two shells. (00:48:35)
Factual error: Simon Phoenix uses the warden's removed eye to escape from the cryoprison. The eye is on a pen, and since the retina includes the back portion of the eye, the pen's nib would have not only destroyed the shape of the retina, but blocked the scanner from reading the complete retina as well. There's no way the retinal scanner would have let him pass. (00:18:45)
Factual error: In the scene where Wesley Snipes has supposedly poured gasoline all over the floor, he lights a torch and holds it inches from the floor threatening to light it if Sylvester Stallone comes any closer. Had it been actual gasoline, with that much of it the fumes would have exploded as soon as he lit the torch. It's the fumes that are explosive, not the liquid.