Continuity mistake: Near the end of the movie, Lara Croft and Manfred Powell (Iain Glen) both draw their pistols and have them pointed at each others head. Powell suggest that the two put the guns down and settle it hand to hand. The two lay their guns down and fight. As the fight is progressing the cave is falling in around them. Laura knocks Powell out and begins to run for the exit and she does not slow down. As she makes it to the exit you can see her pistols in their holsters on her legs. This is edited from a longer sequence, as seen on DVD, but still a mistake in the theatrical release.
Continuity mistake: When Lara is holding onto the arm that has crushed Alex when Powell is saying that they can change his fate, she climbs up, but all of a sudden, she climbs up onto the ground where Powell is walking, and says "You had better be ready for this." If she was holding onto the arm which had stopped due to Alex's body being there how did she get to the ground so fast? You can see from the curve that it is the arm and NOT the ground.
Continuity mistake: During the Fight Scene between Lara Croft and Manfred Powell, after Lara has hit him in the throat and he collapses, she retrieves a locket from his clothing. The next shot is from a different angle, showing his prostrate form with only Lara's legs and waist visible, including the hand that held the locket. Guess what.. it's no longer in her hand.
Continuity mistake: When Lara is bungee-jumping in her house (just before Powell's henchmen break in to steal the clock) she takes her starting jump off the stone barrier upstairs. The shot shows the ropes are attached to the ceiling about a metre in front of her starting position. In the next shot though, she is bouncing from the middle of the room, in front of the central chandelier, so between shots, the ropes attached to the ceiling moved across.
Continuity mistake: When the UPS man walks through the door into Lara's house, there is a close-up of his feet which shows him walking through debris from the previous night gunfight, but a longer shot shows no debris on the floor behind him. Then another close-up shot shows debris in front of him, which looks remarkably like the debris he's just supposed to have walked through.
Other mistake: Towards the end of the movie, Lara Croft and the bad guys are in the frozen ruins of an ancient civilisation. Upon reaching the outskirts of the ruins one of the characters mentions that the ancient city is a "dead zone" which I understood to mean it was an anomalous area where electrical devices wouldn't work - not just no communications, because the vehicles stop working and Bryce's laptop just dies. Once inside the city however, the laser rifle sight worked just fine.
Factual error: In the fight scene in Lara's garage, she rides her motorbike towards the guy attacking her, does a front wheelie and knocks him out with the rear wheel by braking and turning the bike on its front wheel. The back end of the bike then gently lowers itself to the ground, rather than dropping heavily under the force of gravity.
Continuity mistake: What happens to all the men that attack the house to steal the clock? She kicks loads of their arses, and they just disappear.