Resident Evil: The Final Chapter

Continuity mistake: It was briefly stated in the second film that the T-Virus was created by Dr. Ashford to cure his daughter Angela and that the Red and White Queens were based on her. This movie contradicts that by suggesting that Dr. Marcus created the T-Virus to cure his daughter Alicia, and that the Red/White Queens were modeled after her. While the rest of the movie stays true to the continuity of the previous films, this rather obvious ret-con is still a major continuity gaff.

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Continuity mistake: At the first overpass Alice tries to use the motorcycle that's just sitting there, strangely clean. She doesn't have her prints in their system so the bike won't start and she gets zapped. She gets captured by Dr Isaacs and cuts off his left hand to escape on a motorcycle carried on his armored vehicle. Later at another destroyed flyover, she gets back onto the bike and rides towards Raccoon City. No fingerprint or hand required.

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Ladyrebyl
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Suggested correction: She likely used Isaac's hand to access the bike's computer system and either re-programmed it to work with her finger-prints or simply disabled the security system so it wouldn't require a finger-print scan. She was a former head of security with Umbrella and knew how their systems worked and what they could do, after all. It'd be a lot easier to do that than carry around a hand that will likely start to rot, and nothing in the film indicates that wouldn't be possible.

Continuity mistake: There is a scene of Alice being dragged by a line behind Isaacs' tank ahead of a horde of zombies. There is no other line next to running Alice. When she climbs upon the tank to attack the guard, another line with torn hands is seen being dragged on the road, where Alice was dragged.

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Mistakes

It was briefly stated in the second film that the T-Virus was created by Dr. Ashford to cure his daughter Angela and that the Red and White Queens were based on her. This movie contradicts that by suggesting that Dr. Marcus created the T-Virus to cure his daughter Alicia, and that the Red/White Queens were modeled after her. While the rest of the movie stays true to the continuity of the previous films, this rather obvious ret-con is still a major continuity gaff.

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Trivia

Every previous film ended with a dramatic zoom-out starting with Alice that teased the events of the sequel that followed. Appropriately, "The Final Chapter" ends by doing the opposite - dramatically zooming into Alice and ending with an extreme closeup of her eye. This also bookends the series, as she was introduced in the first film with an extreme closeup of her eye opening.

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