Character mistake: In the scene where Carrie is printing an article she has written, the title reads: The Terrible Two's. A successful, educated writer would never have used an apostrophe to pluralize a word. Ever.
Character mistake: Dwanye Johnson is called onto the ice, the first thing he does is throws a player through a glass pane. The player looses a tooth. The close up shows that the tooth is a molar, but the commentators say, seconds later, "Ohhh that's an incisor!" (00:01:00 - 00:02:35)
Character mistake: In the New Orleans scene in the cop car he calls in an officer down and describes the black vehicle as a Tahoe, but it's a GMC Yukon. He also describes the suspect as "Male, black suit and tie" but when he exits the vehicle they are both blue.
Character mistake: After Reed proposes to his girlfriend, he calls Julia and leaves an excited voicemail telling her he has huge news. When Julia listens to what is supposed to be the same voicemail, the wording and tone are completely different, leading Julia to think something was wrong, such as his girlfriend declining the proposal.
Character mistake: When Dale and Allison are playing Trivi-Up, Dale rolls the dice and says "Five". However in the next shot the dice shows "One". (00:24:05)
Character mistake: In the scene when Dave is checking out the failed transmitter at the radio station, Dave says "the bad news is your return loss - way too high". This is a mistake, as the movie makers got confused between the terms "return loss" and "insertion loss". Dave should have correctly said either "your return loss - way too low" or "your insertion loss - way too high".
Character mistake: In the scene where Stewart calls Nicole at the end of the movie, he tells her that he got a horse shot in the leg, when in fact they showed him getting the shot in his neck.
Character mistake: After Gru tucks the girls in for the night, Dr. Nefario tells him that there are 48 hours until the rocket's scheduled launch. The rocket launch, then, should have taken place at night, around the time the girls go to bed, two days later. The rocket, however, launches during daylight hours.
Character mistake: In the scene where Aaron visits Daphne at the hospital, the lower left x-ray in the background is upside down. (00:18:15)
Character mistake: Will Ferrell is talked into shooting his gun at the ceiling. Keaton comes from his office and takes his gun and gives him a wooden one. When he takes the real gun, he unloads the magazine from the gun but fails to remove the round in the chamber. He's a cop, he should know how to safely handle a gun.