Roseanne (1988)
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Starring: John Goodman, Laurie Metcalf, Johnny Galecki, Sarah Chalke, Roseanne Barr, Michael Fishman
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Trivia: Shelley Winters plays Estelle Parsons' mother in the series, even though in real life she's only seven years older than Parsons.
Question: Was Sara Gilbert (Darlene) pregnant in real life when she was pregnant on the show?
Answer: No. Sara Gilbert has given birth to one child (so far) and that was in 2007.