Plot hole: Mayor Tate and Lex have a discussion about bribes and Tate says this is his 4th term (near the end of the episode, Lex is showing Mayor Tate an attack ad which is saying Tate has been the mayor for the past 12 years and Smallville can't afford another 4 years of Mayor Tate, so it's been 12 continuous years). In last season's episode "Crush", Pete gets a job as a summer intern on Mayor Spiegel's re-election campaign. So how is it possible for Tate to have been on his 4th term when in the previous year Spiegel was Mayor?
Continuity mistake: Nell meets up with Lana to talk to her about moving to Metropolis. We see Lana going up to Nell while riding a horse. She then stops and is about to dismount when they cut to another angle but now Lana is dismounting yet again.
Continuity mistake: At Ryan's surprise welcome back party, Clark puts his right hand over Ryan's shoulder as he asks him "you knew about this didn't you?" Cut to a different angle as Ryan responds "I was tempted too" but now Clark's hand is no longer on Ryan's shoulder. Cut to Clark then back to Ryan and now Clark's hand is back on Ryan's shoulder.
Audio problem: After Ryan collapses at Lex's, he and Clark are talking while Ryan is in the hospital. In the shot of Clark as Ryan says "I know what's wrong with me." Ryan's mouth is visible and you can see that he is not speaking the line as we hear it.
Continuity mistake: Lex brings some comic books to Ryan at the hospital. He holds all of them with his left hand. He then shows 66 of the comic to Ryan and holds it with both hands. Cut to a different angle and now he is holding the comics with just his left hand once again.
Continuity mistake: After Clark finds out that Ryan is dying, we see him holding a comic book in the farm. His dad then arrives and he turns to look at him. He places his left hand to his side as he holds the comic book in his right hand. Cut to a different angle and now both his hands are together in front of him.
Answer: No, there is no such character in the comics. He's a "meteor-freak" like all the other baddies on the show. The sound has something to do with him vibrating his vocal cords very fast to create a high-pitched squeal.