Corrected entry: At least one or two tragedies or accidents in each of the three final Destination films are based on real life events. In this movie, Flight 180 was based on Trans World Flight 800, which also crashed right after takeoff, leaving JFK for Paris' Charles de Gaulle airport, and both were carrying a group of students going to Paris on a class trip.
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Correction: Screenwriter Jeffrey Reddick wrote the original speculative script "Flight 180" in 1994 (intending it for the X-Files TV series). The real-life Flight 800 crash didn't occur until 1996. Reddick went on to use his "Flight 180" script to launch the "Final Destination" franchise in 2000, and Reddick has publicly stated that "Flight 180" is not based on the Flight 800 crash. Source: http://bloody-disgusting.com/news/3349248/read-x-files-script-became-final-destination-exclusive.
Charles Austin Miller