Factual error: The Bielski brothers go on a raid of a German post to acquire some "Ampicillin" to treat members of their refugee band who have typhus. Ampicillin is a penicillin derivative that wasn't available until the early 1960's, and in any case, typhus is properly treated with chloramphenicol or tetracycline, antibiotics of different classes from penicillin. Besides, the German didn't have penicillin of any type during World War II.
Continuity mistake: Midway through the movie, when Tuvia and Zus are fighting and the fight ends, Tuvia begins walking up a hill. As he climbs off Zus after the fight, the bottom of his jacket in the back is folded up. As he walks up the hill, the flap is down, but when he gets to the top of the hill and turns around to talk to Zus, the flap is folded back up.