Corrected entry: The one Resident Evil game where the knife is useful. Aiming down and attacking the legs of a zombie will make the zombie fall, allowing you to get in extra hits.
Factual error: Claire finds the Calico M100P twin pistols. In reality these are filled with .22LR cartridge, not with 9mm parabellum as the inventory menu says.
Correction: The knife is useful in all resident evil games, there is a video online showing how to kill the tyrant with the knife in the original resident evil game for example.