Continuity mistake: When John Candy and Steve Martin are travelling from Jefferson City, Missouri to St. Louis they are crossing the Mississippi River to enter downtown St. Louis. This would not have been possible unless the bus driver overshot the entire city and ended up across the river in Illinois.
Planes, Trains & Automobiles (1987)
Trailers
Directed by: John Hughes
Starring: Kevin Bacon, Steve Martin, John Candy, Michael McKean, Laila Robins
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Suggested correction: I agree with the original post. However, there could be several possibilities for this scenario: 1. Road closures, 2. Road construction, 3. Accidents, 4. Detours, and 5. Heavy "holiday traffic" could have contributed to the bus having to enter St. Louis from the east despite coming from Kansas in the west.
Bus Lover: Why don't you take a picture? It'll last longer.
Trivia: Just after Dell sells his shower curtain rings as earrings, he and Neal are eating lunch. Look between the two men and slightly out of focus, is a woman wearing Dell's curtain rings as earrings.
Question: Del was able to get a rental due to having Neil's card. Then, how was Neil able to get a rental card that eventually got him left in the parking lot if he didn't have a card?
Answer: He had multiple cards. He shows the burnt remains when he tries to rent a room.