At the end, Annie Wilkes forces her wounded victim, writer Paul Sheldon, to write another installment in the Misery franchise. While writing, Paul is planning to kill Annie, but the plan is discovered and Paul's ankles are smashed by a hammer by Annie. When Chief Buster, the town's policeman, arrives at the Wilkes Farm, Annie injects Paul with a sedative and throws him into the basement. But as Buster discovers Paul in the basement, he is blasted by Annie's shotgun; she plans to kill Paul and then commit suicide, but Paul urges her that he should finish the last chapter of his book before the time comes.
When Paul finishes the last page, in which the ending is written, he burns it and throws it to the ground. Annie gets panicked, trying to stop the flames with her hand as Paul bashes her hand with the typewriter. A bloody fight ensues between Annie and Paul. As Annie charges him from the back, Paul grabs a heavy statue and slams it on Annie's head, thus killing her. Eventually, except a small limp, Paul is healthy again. While sitting with his agent in a restaurant, he pictures Annie as a waitress with a knife, but this is nothing but a hallucination. Ironically, she tells him that she's his number one fan. He answers: "That's very nice of you".