Mike Whittier: We are Interpol, and in accordance to section 3 we are transporting an international criminal.
Smith Jamison: What criminal?
Agent 47: The man you've been chasing is a killer. A Ghost. Rumor has it that he works for a group known only as "The Organization." So secret, no-one knows it exists. Takes no sides - yet it has ties to every government. Its sole purpose is the training and conditioning of professional killers. These men are selected at birth - rejects, orphans - all of them - unwanted and disposable. They are made experts in every aspect of combat. And programmed for one purpose... To Kill.
Trivia: When 47 crashes through the hotel window and the kids turn around, you can see that they're playing a videogame. The game is "Hitman: Blood Money", the first mission to be exact.