Factual error: The black and white monkeys seen in Africa are in fact Capuchin monkeys. A species native to South America, not Africa.
Factual error: George's "dog", Shep, is an Asian elephant. However, the jungle scenes take place in Africa.

Directed by: Sam Weisman
Starring: Brendan Fraser, Leslie Mann, Thomas Haden Church, Richard Roundtree
Factual error: The black and white monkeys seen in Africa are in fact Capuchin monkeys. A species native to South America, not Africa.
Factual error: George's "dog", Shep, is an Asian elephant. However, the jungle scenes take place in Africa.
Continuity mistake: In the scene where George hits the tree and falls on a branch with green stuff on it, you can catch a glimpse of his briefs.
Ursula's mother: When Lyle returns, this wedding will proceed as planned. If you do anything to upset that, I'll remove your reason for wearing a loincloth.
Trivia: In the scene with George swinging from the Bay Bridge in San Francisco, that's actually Brendan Fraser, not a stuntman. He enjoyed the rush so much that he requested an extra take just to swing again.
Answer: They never mention what ultimately happens to his parents. However it's mentioned they "searched high and low" for George and never found him. The animation even shows all the passengers calling out for George, to suggest they also aided in the search.
Bishop73