Trivia: In the scene where the three men are in jail towards the end of the movie, the jailer that comes to let them out (but is stopped by Ben Stiller) actually plays a cop in the Comedy Central show "Reno 9-1-1". In fact, he may even be wearing the exact uniform he wears in the series. Also, the sheriff deputy who comes off the motorhome yelling "Look, he has rubber boobie!" is also a cop on Reno 9-1-1.
Trivia: The house used as the Focker's home (outside shots only) is the same home used in the TV show "Fantasy Island". The Queen Anne Cottage is located at the Los Angeles Arboretum, even though the movie is set in Florida. The outside of the house was re-dressed and so looks a little different.