Plot hole: How did Dolittle manage to rescue an incredibly heavy bear from drowning? He must be unbelievably strong to be able to drag a bear of that weight. (00:35:25)
Other mistake: In the courtroom scene near the end of the film, the Apple logo on the laptop is upside down.
Factual error: A male bee yells, "attack!" and more male bees cry, "defend the hive!" Male bees never leave the hive and they don't have stingers. (01:02:10)