Osmosis Jones

Osmosis defeats the bad cell (Thrax). Osmosis is hired back on to the police force. Drix decides to stay in Frank's body. Frank starts eating healthier.

Space Moose

Deliberate mistake: The 'NNN' news program shows a picture of some animal crackers in Frank's stomach. The problem is, they are still all in one piece and are pretty big. I don't think Frank would swallow them whole.

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Mayor Phlegmming: Good evening, citizens of Frank. In the past few weeks of the campaign, my opponent has thrown around a lot of fancy words to try to confuse the issues. Words like "exercise", "low-fat", and "diet." Words designed to scare us into changing what has worked for so many years. Well, I say, let's stay the course. Remember, a fat Frank is a happy Frank.
Leah: What? That's not what I wrote.
Mayor Phlegmming: I propose something that every organism in this city will enjoy. I give you a dream vacation to the annual chicken wing festival in Buffalo, New York. Final plans have been made and nothing is going to stand in our way!

Bishop73

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Trivia: In the widely released version of Osmosis Jones in the background of the opening chase scene, a remix of Foreigner's 'Hot Blooded' plays, but in the VHS release it plays Electric Avenue by Eddy Grant.

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Question: What happened to Shane's mom? In one scene we learn that she died because she was sick but what did she have that caused her to die?

Answer: Just like Frank, Shane's mom never ate healthily. Instead, like Frank, she probably just ate whatever she wanted, so she most likely died from a heart attack from eating unhealthy foods or from obesity.

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