Continuity mistake: Look carefully at the brochure Frank has about the Buffalo Chicken Wing festival, the building pictured is the same building as his daughter's school (seen earlier in the movie).
Osmosis Jones (2001)
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Directed by: Peter Farrelly, Bobby Farrelly
Starring: Bill Murray, Laurence Fishburne, Chris Rock, David Hyde Pierce, Brandy Norwood
Genres: Action, Animated, Comedy, Crime, Drama, Romance, Thriller
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Suggested correction: While the buildings might look similar, they are different buildings. The school has 3 levels with rectangular windows with a pyramid top while the building in the brochure only has 2 levels of non-rectangular windows and more of a dome shape on top.
Mayor Phlegmming: Good evening, citizens of Frank. In the past few weeks of the campaign, my opponent has thrown around a lot of fancy words to try to confuse the issues. Words like "exercise", "low-fat", and "diet." Words designed to scare us into changing what has worked for so many years. Well, I say, let's stay the course. Remember, a fat Frank is a happy Frank.
Leah: What? That's not what I wrote.
Mayor Phlegmming: I propose something that every organism in this city will enjoy. I give you a dream vacation to the annual chicken wing festival in Buffalo, New York. Final plans have been made and nothing is going to stand in our way!
Trivia: Thrax is like Morpheous from the Matrix trilogy. His black coat, black glasses and he is even voiced by Laurence Fishburne. In his end fight with Osmosis there is a very clear Matrix reference (the bullettime effect).
Question: If Frank got Anthrax by eating the egg in the monkey's mouth, shouldn't that monkey have been dead anyway?
Answer: We are never told that the monkey was sick with the disease. The egg does fall out of the monkeys mouth and onto the ground where the virus could have easily been on the ground and it just happened to come into contact with the egg.
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