Stephen Hawking: There should be no boundaries to human endeavor. We are all different. However bad life may seem, there is always something you can do, and succeed at. While there's life, there is hope.
Soon after Jane meets Stephen at the beginning of the film she writes her telephone number on a napkin. Later when he looks at the number it is written much more clearly.
Of the 2015 Academy Award nominees, it was the only film to earn nominations in both the Leading Actor and Leading Actress categories.