Plot hole: Lucy jumps from the airliner and flies her hang-glider straight to Eduardo/El Macho's Cinco de Mayo party to find Gru. How did she know Gru would be there? He had no intention of going and only did so after he was pestered into it by the girls on the very night of the party, so he couldn't have told her himself. Shouldn't she have gone to his house instead? (01:09:50)
Continuity mistake: In the scene where Grug is chasing after Guy, they both wind up stuck in a tar pit. After successfully escaping they are covered in tar and Grug even gets himself stuck to Guy. In the next scene everyone is running from the exploding ground up between the mountains and both Grug and Guy are completely clean and free of tar.
Continuity mistake: Lotte barges in the pizza place and carves her name onto Shaggy and Scooby with her sharp nails. LOTT on Shaggy's shirt, and the E in Scooby's fur. They run out the door and then come back to pay for their food. Suddenly the rips in Shaggy's shirt and the scraped off fur on Scooby's chest have vanished. (00:23:45)
Other mistake: Sam draws an orange vest for Lockwood using a dark crayon. (01:10:45)
Plot hole: When Jake first meets Reggie, he tells Reggie that the Great Turkey told him everything about him. Later in the movie, when Reggie goes back in time and introduces himself as the Great Turkey to a young Jake, he only tells Jake to find the "Pardoned Turkey" but never said that the pardoned turkey's name was Reggie, so there's no way the adult Jake would know Reggie's name when they first meet.
Continuity mistake: After Batman shoots Reverse Flash through the head, Flash rushes over to Batman and catches him before he falls over from his wounds. As Flash is lying him down slowly, there is no blood on Batman's face. It then cuts to a close up as Batman reaches up to pull off his mask and there is suddenly blood on his lips and chin. (01:12:20)
Continuity mistake: When Dusty first takes off for the big race his "D7" on the right side of his tail disappears. (00:32:35)
Continuity mistake: In the hotel, at Gagamel's room when Clumsy suddenly opens the food lid and bonks the room service guy. The lid falls at the right side of the door, but in the next shot, when Gagamel opens the door, the lids is on the left side. (00:55:55)
Continuity mistake: As Lex and Joker are talking on the bridge between two towers of Arkham Asylum, Joker is shown standing in the middle of the bridge. But when the guy on the intercom announces there is an escape going on, the camera changes angles and suddenly Joker is right next to the edge. (00:19:20)
Continuity mistake: As in most movies I've seen where size is a main factor, the animators did not pay much attention to scale. In the scene where the main character leads the leaf people to her father's house, she is jumping and lands on the thinnest pencils I've ever seen. They have the width of the pencil smaller than her foot. However later on, it is shown that a push pin is almost the size of her body.
Plot hole: Luka sneaks into Bayonetta's hotel room and plants a hidden microphone. While sneaking out, he is caught. That's when he is astonished to find a child with Bayonetta who calls her "mummy." He does eventually escape the room and sits in corner with his radio, surprised that they both went to bed and he receives nothing. The problem is: One must be an idiot to plant a mic in a lone woman's hotel room in the dead of the night, unless he truly enjoys listening to her snoring! Planting the mic in her apartment or office, or on her mobile phone makes a lot more sense.