Continuity mistake: Season 4, episode 13 "Thanksgiving": During the East vs West football game, the East Dillon Panthers are wearing their white uniforms. However, in a quick shot of the Panther coach talking to one of his players on the sideline, the Panther players are wearing their blue uniforms. When the shot goes back to the play on the field, they are back in the whites.
Other mistake: Coach Taylor and Tami moved to town before the season. Tami is asked to work on the mayor's reelection campaign. Coach Taylor asks Tami "Does she know you voted for her opponent?" This wouldn't be possible as the previous election would have occurred years before the Taylors moved to town.
Continuity mistake: When Tyra enters Principal Taylor's office to tell her that she has just been elected student body president she has a purse on her right shoulder. Half way through their conversation the purse disappears and when she leaves the office she takes nothing with her.