A Very Supernatural Christmas - S3-E8
Revealing mistake: When the boys are tied up and the pagan gods are preparing for the ritual, the second time they cut into Dean's arm the knife is pressed along his arm and the blood is removed showing no cut at all.
Answer: Over the next few episodes, it is revealed that something is not quite right with Sam - that his soul is missing since he returned from Hell, and he does not feel any emotion or attachment to his brother.
Sierra1 ★