MikeH

Answer: The actor was diagnosed with cancer and was going through treatment, and was physically unwell. As a result, he had to drop out of multiple projects, including "Malcolm in the Middle." He sadly passed away five years later.

TedStixon

Answer: Because the actor died unfortunately.

He actually died five years after the show ended. It was because he had cancer and was going through treatment, and was physically unable to continue doing some of his roles.

TedStixon

Answer: Start to end Malcolm: 11 - 17 Francis: 16 - 23 Reese: 13 - 19 Dewey: 7 - 13.

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