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Trivia: SPOILER: When Wanda kills Professor X inside the mind of her possessed alternate self, it first appears that she snaps his neck. However, if you watch it in slow motion, you can see she actually rips his head in half.

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Trivia: After Gargantos throws Strange through the store window and refocuses its attention on America Chavez, the music that is playing is an homage to Modest Mussorgsky's "Night on Bald Mountain."

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Trivia: The identity of the film's main antagonist was the subject of much speculation in the months leading up to its release. Nightmare was rumored, and the release of a toy line for the film showed action figures for the characters Sleepwalker and D'Spayre, neither of whom actually appear in the film.

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Trivia: The six members of the Illuminati in the film are Mordo, Maria Rambeau, Captain Carter, Reed Richards, Professor X, and Black Bolt. The latter three are also members in the comics, however, the other three slots in its original incarnation were occupied by Doctor Strange, Namor, and Iron Man.

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Trivia: This film was banned in Saudi Arabia due to Disney's unwillingness to cut 12 seconds of dialogue in which the character America Chavez mentions having two moms.

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Trivia: SPOILER: This marks the first appearance in film for a member of the Inhumans, with Black Bolt being a member of the Illuminati. The Inhumans were originally supposed to have their own movie as part of the MCU's phase 3, but it was scrapped and adapted into a negatively received TV series on ABC, which was canceled after one season. Anson Mount, who plays Black Bolt here, also played Black Bolt in the TV series.

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Trivia: When Doctor Strange and America Chavez first travel through numerous universes, they pass through a space showing multiple heads with glowing eyes. This is the Living Tribunal, who was referenced in the first film.

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Trivia: After 22 years and a dozen film appearances, this is the first time Professor X is shown using his iconic gold hoverchair from the comics and 90's X-Men animated series. He is also wearing a green suit jacket with a black and blue tie, which were what he wore in the aforementioned series.

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Trivia: This is the first MCU film in which clips from a TV series - specifically WandaVision - are part of the Marvel Studios logo during the opening.

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Trivia: Doctor Strange casts a spell on the pizza vendor, played by Bruce Campbell, that forces him to repeatedly hit himself. This is similar to a scene from Evil Dead II, which sees Ash, also played by Bruce Campbell, attacked by his own possessed hand.

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Trivia: During Strange's meeting with the Illuminati, Professor X says that just because someone stumbles and loses their way, it doesn't mean they are lost forever. He says the same thing to his younger self in X-Men: Days of Future Past.

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Trivia: SPOILER: Doctor Strange sarcastically asks Reed Richards if the Fantastic 4 had chart-toppers in the 1960s. This is likely a reference to the Fantastic 4's comics debut being in 1961.

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Trivia: SPOILER: This is the first MCU film to feature characters from Fantastic 4 and X-Men (Scarlet Witch and Quicksilver's association with X-Men in the comics notwithstanding). These properties were previously unavailable to Marvel Studios, as their film rights were held by Fox prior to their acquisition by Disney in 2019.

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Trivia: Patrick Stewart revealed in January 2021 that he had conversations with Marvel Studios President Kevin Feige about reprising his role of Professor Charles Xavier in the MCU. Stewart claims to have declined, reasoning that he felt his appearance in Logan was a fitting end to his time as the character, but it appears that he was either fibbing, or later changed his mind.

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Trivia: The version of Doctor Strange seen at the very beginning of the film has been dubbed "Defender Strange." This is because his outfit is taken from the comics when he was a member of the Defenders.

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Trivia: SPOILER: The woman who approaches Doctor Strange in the mid-credits scene is Clea, who in the comics is one of Strange's disciples and love interests. She is also Dormammu's niece, in the comics at least.

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Trivia: The 1973 Oldsmobile Delta 88 that is featured in nearly every Sam Raimi film can be seen floating in the air when Doctor Strange and Christine first arrive in the universe of the corrupted Doctor Strange.

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Trivia: When Professor X first appears onscreen, he is accompanied by the theme from the 90's X-Men animated series. This is the first live action film to adapt this theme. The Fox X-Men films ironically never used it, despite also producing the aforementioned animated series.

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Trivia: SPOILER: Prior to his appearance here, John Krasinski was a popular fan pick to portray the MCU version of Reed Richards/Mr. Fantastic. His wife Emily Blunt has also been a popular fan pick to play Reed's wife Susan Storm/Invisible Woman. Blunt has said the role does not interest her, but actors in past MCU projects have been known to mislead about their involvement.

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Trivia: The large tentacled creature with one eye is Shuma-Gorath. Due to rights issues over its name, it will be known as Gargantos in the film instead.

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