Continuity mistake: After the library scene, while the three scientists are walking and talking, a woman in a striped blue and yellow sweater passes by Egon, but disappears in the immediate next angle.
Revealing mistake: There's a scene where Dana's building is falling apart and stones and stuff are falling to the street below. One of the huge boulders bounces off a wooden police barricade in the bottom left hand corner of the screen.
Trivia: Casey Kasem does a voice-over cameo as himself on his radio show after the Ghostbusters become famous. The ditsy blonde woman that Louis dances with at his party is played by Casey's wife, Jean Kasem.
Ray Stantz: Everything was fine with our system until the power grid was shut off by dickless here. Walter Peck: They caused an explosion! Mayor: Is this true? Peter Venkman: Yes it's true. This man has no dick.