Trivia: During the opening sequence when the giant magnet ship steals the PX-41 research building, one of the researchers falls and yells a Wilhelm scream.
Plot hole: Lucy jumps from the airliner and flies her hang-glider straight to Eduardo/El Macho's Cinco de Mayo party to find Gru. How did she know Gru would be there? He had no intention of going and only did so after he was pestered into it by the girls on the very night of the party, so he couldn't have told her himself. Shouldn't she have gone to his house instead? (01:09:50)