Revealing mistake: At the beginning of the movie, when Melvin catches Simon's dog, he holds it away from him, with his arms stretched. When the dog begins to pee, you can see that the urine is coming out from Melvin's glove. (00:01:30)

As Good As It Gets (1997)
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Directed by: James L. Brooks
Starring: Jack Nicholson, Cuba Gooding Jr., Greg Kinnear, Helen Hunt, Skeet Ulrich
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Melvin Udall: Judging from your eyes, I'd say you were fifty.
Carol Connelly: Judging from your eyes, I'd say you were kind, so so much for eyes.
Trivia: Betty White was originally cast to play Helen Hunt's mother, Beverly Connelly, but she objected and withdrew from the role because the beginning of the movie has Melvin Udall dumping Verdell down the garbage shoot. Betty White is a huge animal rights activist.
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Answer: It has everything to do with his mental illness. His OCD condition has kept him isolated with anti-social tendencies. He just finds it difficult to directly interact with people.
raywest ★