Continuity mistake: In the very first shot of inside the orphanage, the tape mark on the floor is at least 3 feet away from the desk. The three girls stand behind it and 2 shots later we can see they are standing about an inch away from the desk. Then when Miss Hattie stands up, the tape is now a foot away from the table.
Continuity mistake: Justin, the boy with the toy aircraft running away from his mother, towards the pyramid in the beginning of the movie, has the toy in his left hand while going up the ramp, while falling and as he begins traveling up through the air but when the angle of view changes it is in his right hand until he lands on his father. (00:02:05 - 00:02:45)
Continuity mistake: The girls shoot the freeze ray at Gru and he gets covered in ice. After his flashback he falls back and the ice shatters. But when Gru says "But I...", the ice has disappeared.
Suggested correction: Actually, the ice is still there, it's just out of view.
While it is out of view, that would mean it'd be visible in the reflection of the TV screen when it turns off. But it isn't. Therefore, it does disappear.
The only thing that can be seen when the television turns off is a very faint reflection of Gru. It is impossible to tell if the ice is or isn't there.
Yeah, though ice is just not in the camera view.
Continuity mistake: When Gru is explaining his plan to the minions, one of them takes out a torpedo and fires. The torpedo is held by one of the taller minions at first, but after the torpedo has fired and Gru says "Hey, Dave", we can see the torpedo was held by one of the smaller minions.
Suggested correction: The minion holding the torpedo was a small one all along. The taller one is probably just one in the crowd. If you look closely when the minions grab their weapons, Dave, the one who held it in the first place, is a short minion holding a torpedo.