Galaxhar(Rainn Wilson) captures Susan(Reese Witherspoon) and drains the Quantonium from her, making her small again. The Missing Link(Will Arnett), B.O.B.(Seth Rogen), and Dr. Cockroach(Hugh Laurie) get into the ship and free Susan. They manage to hack into the spaceship's computer and set the ship for self-destruct. This causes the ship to lockdown, seperating Susan from the other monsters. She breaks into the control room and fights Galaxhar. Galaxhar tells Susan that he can't override the lockdown and can't free the monsters. Susan sees that Galaxhar has drained the Quantonium into a glass ball and knocks it loose so that it lands right on her. Susan becomes giant again and saves the monsters. They escape the ship before it blows up, courtesy of Insectosaurus, who has sprouted wings, like a butterfly. General W.R. Monger(Kiefer Sutherland) tells the monsters that there is a monster terrorizing Paris. They all get on Insectosaurus' back and fly off....
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